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Joined 3 years ago
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Cake day: June 19th, 2023

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  • I get it, I do. It’s that may or may not that makes the difference. Pcos is enough of a health risk of its own that the drawbacks of spironolactone are generally worth it, and when combined with other hormonal supplementation, can end up with a net improvement in overall health. But it takes monitoring for it to be fully safe.

    We’re not talking about minor dizziness and such. It’s the liver and kidney damage that’s the main factor in making it a poor choice for unmonitored use. By the time you catch the effects without regular testing, the damage done can be life threatening.

    And, if it jacks up your potassium levels, you might not even get that much warning. People do go into cardiac arrest from it. It isn’t common, but it happens.

    My sister was on it for a while, for pcos, and it caused long term problems despite being monitored. It’s a great drug with careful use, it saves lives as a diuretic. Or at least prolongs them. But it is most definitely not something to self administer.

    Something like flutamide is way safer, and has less side effects in general. But, again, without knowing pcos is in play, you’ve got a really high chance of wasting money you could put to other treatments, or getting second or third opinions to determine what is in play.

    It’s a numbers game. What is going to give you the best results with the least risks, for the least resources used. The estradiol at least has minimal short term risks, so I can see the equation shifting to trying it to see if it helps. No telling if the probability of that is high or low without knowing what traits are unwanted that you’re trying to shift, but at least it won’t kill you in the process if things go wrong. Well shouldn’t, since bodies can have some weird shit happen sometimes, but it’s not a significant risk.

    If I was being a patient advocate for someone in my life, I’d be steering them towards other options even if they were being monitored medically. It’s my opinion that the only real benefit of spiro for DIY hrt is the price/availability factor. It’s usually affordable, and easier to get. And, for someone transitioning or dealing with something like prostate cancer, it would make sense because of the higher androgen production. For a cis woman, even with pcos, I just couldn’t advise it in good conscience.

    But, to be clear, I totally support self care when the system fails. The issues you’re dealing with are significant and important. I just really think you’d be better served with a different plan of action.


  • I’m going to echo the doubts about spiro being either useful or appropriate in this case. It’s really not ideal for what you’re trying to achieve, and even if it were, the risks are far out of proportion to the benefits it could bring for a cis woman with some kind of androgen issue.

    The estradiol? Eh, the risks involved are within the range I’d say make it up to the individual as to being worth it, but I kinda doubt you’ll get what you want out of it, at least not without knowing exactly why you picked it. It’s not something I would recommend for a cis woman trying to reduce masculine features, as it tends to be weak in that regard. Not that it can’t do anything, it’s that a cis woman with normative levels isn’t going to get extra benefits.

    But the spiro , you should just donate to someone in need. It’s really not going to help you, and it can hurt you.

    Besides, doubling up new meds is a bad idea. You have to play smart so that you not only know what is working and isn’t, but can identify what’s causing any problems that arise. If you insist on using both, at least stagger their onset out by a few weeks so you can get a better idea of whether or not one is doing anything bad.

    Going DIY with any med is iffy. So if any given person is going to do it, you have to use more caution than a prescribing doctor would, not less. You can’t get in a rush with this kind of thing.


  • Ngl, there’s still plenty of assholes in the current crop of under 30s and under 20s.

    But, yeah, there’s a lot more of this kind of acceptance and decency. It’s a beautiful thing to see. I got to see a similar wave of change back in the nineties with gay people, men in specific, where the millennials were essentially defaulting to acceptance or outright active support. For my generation, we had a longer road to divest ourselves of outdated thinking, so watching acceptance spread was a different experience than watching the next generation just grow up without as much baggage.

    Again, no generation has ever, or will ever, be a monolith of bottled belief. But it does seem like the curve of decency on average is looking really damn good right now.




  • Only reason I went with the speed boat was the claim to fame of the falcon being able to veritably rip through the Kessel run. Depending on the interpretation of the whole “12 parsecs” thing, that implies either high speed or superior maneuverability. Plus, in some of the combat scenes, the falcon is both fast enough and nimble enough to hang with ships that are zipping around with little effort.


  • southsamurai@sh.itjust.workstoRisa@startrek.websiteNo contest
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    2 months ago

    I don’t think vintage van is apt.

    I think I’d go more with the something like a juiced up truck, or maybe hummer.

    However, you could make the more apt comparison by sticking with ships.

    The falcon was a smugglers’ ship, so it would be more like one of those fast cigarette boats drug runners use (or used to at least) rather than a car at all.



  • It’s that the objection to the choice of “hormone replacement therapy” for gender affirming care is malarkey. Yeah, the term for those medications started for people that have a deficiency in a given hormone, typically as an age related issue. But that doesn’t negate it when used for replacing one variety of hormone for another.

    In other words, the argument that it isn’t replacement therapy when the levels of existing hormones are normative for a person with a specific type of gonad that are fully functional misses the point that it’s still HRT, just a slightly different semantic expression of it.







  • Legit, that idea always bugs me. On multiple levels.

    For one, a person’s value isn’t in looks to begin with. Then, there’s the misogyny of it, reducing women, yet again, into objects of the gaze (it isn’t just the male gaze, and it isn’t always a sexual thing when it is, and my objection to the idea goes beyond that part).

    Like, damn, how shitty someone has to be to even think that thought, much less speak it.

    But there’s also the smugness that their idea of beauty must be the right one, and the only acceptable one. Fuck off with that shit.

    The old adage of beauty being in the eye of the beholder is more than an adage. Just because their punk ass can’t see beauty doesn’t mean it isn’t there to be seen. Yeah, there’s ranges of features and traits that are going to appeal to different percentages of the population, but that still doesn’t mean any given person’ opinion of those traits is inherently superior.

    People can really suck


  • southsamurai@sh.itjust.workstoFediverse@lemmy.world*Permanently Deleted*
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    3 months ago

    Kinda depends on what features in sync made you like it.

    Overall, boost, connect, thunder and summit each get close to parity, but only close. But, you could say that in reverse, (that sync only gets close to parity with any of them) it isn’t a slight against any of them.

    Eternity is another one that I’ve had good use of, but development on that seems to be stopped as well, so I dunno if that’s a useful option.

    Past those, you get less similarity in ux and ui than would make sense to compare. Like, the apps that mimic voyager (or whatever the popular iOS reddit app was called), things are laid out so different that if you used sync as a primary, you aren’t likely to enjoy that ui.

    On a phone, I kinda favor connect over sync, despite it looking very unlike it compared to boost or eternity. But on a tablet, nothing else does double columns in portrait worth a damn for me, and aren’t great in landscape either. But boost and eternity come the closest to the visual ease sync has.

    The sync visual that’s sync

    I was going to include screen shots of the ones I have on this tablet, but uploads shit the bed and are being weird after that one. So no promises that I can do them all

    boost boost

    eternity eternity

    connect connect

    interstellar and interstellar since it does piefed better than anything else I’ve tried, and still does lemmy just fine.

    Decided to install thunder and summit long enough to give a visual

    thunder thunder

    summit annnd summit

    As you can tell, everyone has a slightly different approach to the UI. But they’re even more variable in what settings are available, little niceties, etc. Theming is all over the place from a bare bones light/dark/oled to the relative broad visual options of boost and sync. None of them are bad at all. They’re reliable, work even on older devices without bogging them down, and are all easy enough to get going with.


  • One problem

    Batteries.

    I’ve used old devices as many things: security cameras, a form of intercom, digital picture frames, etc. The real problem is that the batteries eventually go bad, and become dangerous.

    For the few devices that have realistically replaceable batteries, that’s no big deal, but how many of those are left now?

    No thanks to the potential fire, I’ll pass. The few devices I have left that I can swap batteries out are becoming harder to find new batteries for as well, so that’s an issue beyond their anemic hardware (I’m talking really old tablets at this point)



  • I may be crazy, but yeah. I think things will eventually swing back to people not being giant shit bags about things that aren’t their business.

    The problem is when, and how much struggle between. I don’t think it’ll be long on the scale of things because once awareness hits a given threshold where the abstract becomes personalized, humanized, it’s a lot harder for hate to keep going.

    I’m fairly confident that the us and most of Europe had hit that threshold. That should be enough to keep things from regressing totally, which means an eventual resurgence of acceptance and integration into societal mores.

    Not that there is ever likely to be an absence of bigotry, and there won’t ever be an absence of ignorance, much less outright “sociopathy” where people actively seek a target they can hate and abuse.

    Social progress is rarely linear. There’s fits and starts until things start chugging forward steadily. It was like that with pretty much every rights movement I know of, so I don’t see why trans rights should be an exception.