okay so the process isnt that painful or cold for me, but i have high pain tolerance, however i hear the same from near everybody who does it.
im using estrodiol enanthate, there are different formulas that will have different doses, my dose is about 5mg of estrodiol a week, and that ends up being a rather small amount of actual liquid for my formula. there is a really good calculator for different formulas and doses here https://transfemscience.org/misc/injectable-e2-simulator-advanced/
i aim for the outer thigh, around where the muscle is closer to the skin than the fat, but some people do it in the butt, or stomach. there are two kinds of injections, im doing inter muscular, or straight down 90 degrees from the leg, but there is also sub dermal, where you go at 45 degrees and less deep. for my injections i go an inch deep or more.
i hold the needle like a dart, and do it all in one swift motion, stretching the skin and coughing as it breaks skin, it helps to not notice the prick of the needle. going in one swift and smooth motion is best, going slow hurts more. then i press down on the plunger and pull it out when im done.
there are more steps, this is the simplified version, there are much better tutorials online, i just wanted to answer some of you questions directly.
I’m sure there’s a risk of them but I don’t have any yet after a month, and I switch legs every time